2. Signaling Pathways
  3. Immunology/Inflammation
  4. Toll-like Receptor (TLR)
  5. Toll-like Receptor (TLR) Ligand

Toll-like Receptor (TLR) Ligand

Toll-like Receptor (TLR) Isoform Comparison

Toll-like Receptor (TLR) Ligands (5):

Cat. No. Product Name Effect Purity
  • HY-153879
    C12-TLRa
    		Ligand 99.0%
    C12-TLRa is an ionized adjuvant lipid. C12-TLRa targets TLR7/8 receptors in endosomes. C12-TLRa enhances mRNA delivery as a structural component of LNPs. C12-TLRa enhances innate immune responses. C12-TLRa can be used for the research of SARS-CoV-2 mRNA vaccine.
  • HY-D1056C5
    Lipopolysaccharides, from S. enterica serotype minnesota Re 595 (Re mutant)
    		Ligand
    Lipopolysaccharides (LPS), from S. enterica (Salmonella enterica) serotype minnesota Re 595 (Re mutant) is prepared from Salmonella enterica strain Re 595 (Re mutant). The structure in the LPS of strain Re 595 was shown to induce secretion and aggregation in human platelets.
    It is recommended to prepare a solution with concentration ≥2 mg/mL. Vortex thoroughly for more than 10 minutes. Due to the adsorption characteristics of LPS, silanized container or low adsorption centrifuge tubes should be used for aliquoting and storage, and mix thoroughly before use.
  • HY-174465
    TLR4L 10
    		Ligand
    TLR4L 10 is a TLR4 ligand. TLR4L 10 induces cells to produce IL-6. TLR4L 10 has immunostimulatory activity.
  • HY-171239
    Ste2Cys
    		Ligand
    Ste2Cys is a diacylglycerol cysteine-type immunologic adjuvant lipid molecule. Ste2Cys can bind to TLR2 and activate NF-κB signaling pathway. Ste2Cy can upregulate the expression of MHC II class molecules on the surface of mouse bone marrow-derived D1 dendritic cells. Ste2Cys can be used for research of the development of immunologic vaccines.
  • HY-167966
    Mal-TLR7 agonist 32
    		Ligand
    Mal-TLR7 agonist 32 is a drug-linker conjugate that consists of a TLR7 agonist (HY-167774) and a linker. Mal-TLR7 agonist 32 can be used in synthesis of ADC.